Dr. Gladden’s Arterosil Study Results

Dr. Gladden’s Arterosil Study Results

Arterosil HP is an all-natural dietary supplement designed to support the body’s
vascular system for its optimal functions. In a previous human clinical
study, ArterosilHP was demonstrated to protect the endothelial
glycocalyx, the micro-thin slippery inner lining that prevents all blood
vessels from damage, in healthy subjects after they consumed a
standardized high sugar high fat meal. At the same time, the subjects
showed improved endothelial function with ArterosilHP supplementation as
measured by reactive hyperemia index (RHI).

In the current study, we hypothesize that ArterosilHP rapidly improves
arterial elasticity and pulse wave reflections through enhancing the
endothelial glycocalyx and its mediated arterial function. Nineteen
healthy human subjects (11 females age 22 to 64 and
8 males age 30 to 60) were randomly recruited for the open label single
blinded clinical study, which was co nducted at an independent
cardiology center on the Baylor Medical Campus in Plano, Texas. Their
vascular health condition was evaluated by using an FDA approved pulse
wave velocity diagnostic device, Max Pulse. The subjects arrived at the
clinic in the morning. Their baseline Max Pulse reading was taken at
approximately 2 hours (+/- 30 minutes) post consumption of a breakfast
of their choice. Immediately after the baseline reading one capsule of
ArterosilHP was swallowed. A post-dose Max Pulse reading was taken every
30 minutes for 3 hours, for a total of 7 Max Pulse readings (baseline,
30 min, 60 min, 90 min, 120 min, 150 min & 180 min +/- 5 minutes).
No food or liquid (other than small amounts of water as needed) was
consumed during the 3 hour testing period.

During each of the 7 tests for each subject the follow data were collected:

Percentage of Type 1 Wave Forms
Arterial Elasti city
Stress Resistance
Frequency Domain Power

Results

Percentage of Type 1 Wave Forms

84.2% of subjects experienced an increase in percentage of Type 1 Wave Forms
Average increase in percentage of Type 1 Wave Forms was 48.4% (p = .0032)
Mean time to maximum increase was 114 minutes

Arterial Elasticity

78.9% of subjects experienced an increase in arterial elasticity
Average percentage increase in arterial elasticity was 89.6% (p = .0081)
Mean time to maximum increase was 118 minutes

Stress Resistance

89.5% of subjects experienced an increase in stress resistance
Average percentage increase in stress resistance was 133.3% (p = .0016)
Mean time to maximum increase was 130 minutes

Frequency Domain Power

84.2% of subjects experienced an increase in frequency domain power
Average percentage increase in frequency domain power was 37.8% (p = .0003)
Mean time to maximum increase was 141 minutes

Conclusion

The current clinical study demonstrates that ArterosilHP supports arterial
health by rapidly improving the body’s percentage of type 1 wave forms,
arterial elasticity, stress resistance and frequency domain power. These
findings are consistent with our previous clinical results showing the
beneficial effects of ArterosilHP on the endothelial glycocalyx and
arterial function. Further analysis of these data will help us
understand the mechanisms and design new studies to evaluate long term
benefits of ArterosilHP supplementation on cardiovascular and
micro-vascular health.

In Best Health,

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